Silica Gel Column Chromatography
Column chromatography is used for separating and purifying the liquids and solid compounds. It is an effective chromatography technique in which stationary phase adsorbs the unwanted compounds and other impurities using silica gel and activated aluminum oxide powder as powerful adsorbents. Here, the mobile phase allows the desired compounds to be passed through. It simply means that this separation technology consists of two phases which helps in the separation of mixture of chemicals by its components. It allows the mixture to flow down through the column by either the gravity or by the external air pressure.
Silica gel column chromatography depends on the activity of the silica gel as an adsorbent and polarity of the mixture. With low polarity of the mixture and strong adsorbent activity, it provides highly effective separation of the compound. But at the other end, if there is high polarity of the mixture and high activity of adsorbent, the separation result would not be up to the mark. Silica gel for the separation is used in different methods of chromatography. They include analytical, preparative, process and gravity chromatography. The different size and amount of silica gel is used based on the type of method and the other requirements.
This type of separation, purification and isolation process of synthetic compounds is commonly used in industrial research laboratories and organic synthesis labs. It is required to use quality silica gel in order to achieve excellent results. This type of separation technique is also used in steroids, amino acids, dyes and pharmaceutical intermediates. Just select the most suitable mesh size of silica gel as per the particular application and get the desired outcome.
Benefits of Silica Gel Column Chromatography:
- Optimize separation efficiency
- High adsorption capacity with large surface area
- Reproducible performance
- Suitable for large scale applications
- Excellent flow rates
- Direct scalability
Sorbead India offers quality silica gel for separating and purifying the mixed compounds using the column chromatography. Our manufactured silica gel adsorbent is available in variety of grades and pore sizes at the most competitive prices. Our products ensure to deliver highly efficient outcome for the adsorption, separation, cleanup and purification of range of synthetic and natural compounds.