Use of Silica Gel in Flash Chromatography

Use of Silica Gel in Flash Chromatography

January 28, 2017

Flash Chromatography – An Introduction

Flash chromatography is also known as “medium pressure chromatography”. This form of chromatography works by air pressure driving the mixture, which is to be separated down the vertical glass column. This type of chromatography is ideal for separations that need to take place in a fast paced manner.

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thin layer chromatography

Silica Gel Desiccants in Thin Layer Chromatography

September 27, 2016

Understanding Thin layer Chromatography

Thin layer chromatography is a widely used form of chromatography. This type of chromatography mainly finds use in the separation process of non-volatile mixtures. Thin-layer chromatography consists of both a stationary phase as well as a mobile phase. The stationary phase is usually an adsorbent like Silica Gel, Aluminium Oxide or Cellulose. The thin-layer chromatography process works by the molecular adsorbent like Silica Gel absorbing the different components of the mixture, which has to be separated, at different levels. The adsorbents for thin-layer chromatography are always decided in such a manner that they will quicken as well as improve the separation as well as the subsequent purification process.

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Different types of Silica Gel Chromatography

May 6, 2016

Chromatography – A Brief Introduction

Chromatography is a method widely used in the separation of different compounds, solid and liquid. This method is very helpful in segregating and purifying various components of mixtures, which when separated can be analyzed individually. The chromatography process is a very simple method of separating compounds using a solid as well as liquid phase. Silica gel, alumina oxide is mainly used as the solid phase, which adsorbs all the unwanted particles as well as all kinds of impurities. When the mixture passes through the mobile phase, then only the required compounds move forward while the unwanted components of the main mixture are left behind.

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Thin Layer Chromatography

Thin Layer Chromatography and Its Many Uses

December 22, 2015

What is Thin Layer Chromatography?


Similar to Silica Gel Chromatography, Thin Layer Chromatography is another procedure used to separate individual components from a mixture. Thin Layer Chromatography also consists of a solid or stationary phase like a silica gel plate and a mobile phase. The Silica Gel acts like an adsorbent for thin layer chromatography. The mobile portion can be a solvent or a solvent mixture, which moves upwards using capillary action. The components that are to be separated are adsorbed at different levels and finally collected at the lower end of the Thin Layer Chromatography or TLC plate.

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Silica Gel Column Chromatography

The Benefits of Silica Gel Chromatography

January 27, 2015

Silica gel adsorbents are widely accepted as one of the best adsorbents that are used in column chromatography. One of the main benefits is that it has a huge affinity for absorption; besides, it is very easily available commercially in many different forms and sizes and there is a lot of research and information that is provided by the manufacturers on its numerous uses, especially in chromatography.

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Why Flash Chromatography method is inexpensive and quicker?

August 11, 2014


After the process of chemical synthesis, the compounds of interest need to be purified in a proper manner. Some of the popular purification techniques are Crystallization, Separation, Filtration, Liquid-Liquid clean up and Distillation. All these techniques are vastly used in the laboratories. But there is another purification method that is used for separating two almost same nature substances. This process known as Flash Chromatography.

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Flash Column Chromatography for Organic Chemistry

Flash Column Chromatography for Organic Chemistry

June 12, 2014


Silica gel is the most commonly used desiccant in the food and pharmaceutical packing industry. It is US FDA approved and also very safe. Silica gel is also called silica aerogel or hydrated silica. Silica gel, along with being a good desiccant in food packaging industry is also used in many procedures in chemistry. It is used in chromatography as a stationary phase. Different particles of different sizes are used for achieving a desired separation of certain molecular sizes in the process of column chromatography. Silica Gel Powder is used in Pharma & Chemical Research Laboratories for column chromatography.

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flash chromatography process

How TLC Grade of Chromatography is used?

June 10, 2014


Chromatography is said to be the best technique which is used to separate compounds form any substance. This is an efficient technique which helps to know that what all constituents are combined to make that substance. This has made the work of scientists easy for various processes. This process can be followed for the identification of compounds in both organic as well as inorganic substances. Depending on the product intensity and molecular placement different technique of chromatography can be used.

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